Case Studies
TYMPANOJUGULAR PARAGANGLIOMA – CAREFUL COMPLETE BLOODLESS DISSECTION OF THE TUMOR IS THE MANTRA; DURATION OF SURGERY IS IRRELEVANT!!
Case Studies
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Articles, Chapters and Books
Publications by Dr. Rao
Throughout his career, Dr. Rao has been able to research and study an array of health care topics. Over the years, he has had the opportunity to publish some of his work in various peer reviewed medical journals and news sources.
He has published in almost all the important journals in his specialty including Neurosurgery, Journal of Neurosurgery, Skull Base, Head & Neck, Journal of Craniofacial Surgery, Otology & Neurotology, Audiology & Neurotology, European Archives of Otorhinolaryngology, American Journal of Otolaryngology-Head & Neck Surgery, Clinical Otolaryngology, Current Opinion in Otolaryngology Head & Neck Surgery, Laryngoscope, Otolaryngology Head & Neck Surgery, Annals of Otology Rhinology and Laryngology, Acta Otolaryngologica, Archives of Otorhinolaryngology, Auris Nasus Larynx, Journal of Laryngology & Otology, ENT Journal, International Journal of Pediatric Otolaryngology, Indian Journal of Otolaryngology, Acta Otorhinolaryngologia Italia, Indian Journal of Pathology & Microbiology, International Journal of Microbiology, American Journal of Forensic Medicine and Pathology, International Medical Case Report Journal, Case Reports in Otolaryngology, Medical Journal of Malaysia, Pone, Acta Neuropathologica.
Over 50 of his publications have been original research (cases series). His total publications including abstractions and non peer reviewed articles stand at 100. He has also written 25 chapters in international textbooks. He has co-authored a textbook on Cochlear and other Auditory Implants.
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Dr. Rao is a reviewer for the following journals
Journal Reviewerships
1. Neurosurgery, Oxford University Press, UK
2. Skull Base (JNLS part II), Thieme Medical Publishers, Stuttgart, Germany
3. Head & Neck, John Wiley & Sons, MA, USA
4. Otolaryngology - Head and Neck Surgery, CA, USA
5. American Journal of Otolaryngology Head and Neck Medicine and Surgery
6. European Archives of Oto-rhino-laryngology, Springer, Berlin, Germany
7. Clinical Otolaryngology, John Wiley & Sons, MA, USA
8. Laryngoscope, John Wiley & Sons, MA, USA
9. Journal of Otology, Elsevier, The Netherlands
10. Annals of Otology, Rhinology & Laryngology, Annals Publishing Company, MO, USA
11. Acta Otolaryngologica, Taylor & Francis Group, Informa UK Limited, London, UK
12. Acta Otolaryngologica Italia, Società Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale,
Italy
13. International Journal of Otorhinolaryngology, Thieme Medical Publishers, Stuttgart, Germany
14. Ear Nose Throat Journal, Vendome Group, NY, USA
15. BMJ Case Reports, BMJ Publishing Group, London, UK
16. International Journal of Audiology, Informa Healthcare, London, UK
17. Indian Journal of Otolaryngology – Head & Neck Surgery, Springer, India
18. Saudi Medical Journal, KSA
19. Cancer Treatment Research, Elsevier, USA
20. Journal of Medical Case Reports, BioMed Central, UK
21. Karbala International Journal of Modern Science, Elsevier, Iraq
22. International Research Journal of Medicine and Medical Science, Net Journals, South Africa
Journal editorial board member
1. 'Advances in Otolaryngology', Hindawi Publications, Egypt & USA.
Research scores & impact points
(till date)
Research Gate
RG score: 36.56
H index: 16
34,390 reads
774 citations
Google Scholar
Citations 1113
h-index 17
i10-index 32
Peer-reviewed publications
Here are some of the most important of Dr. Rao's publications
Of the 100 publications, over 50 are original research (cases series). Dr. Rao has also written over 20 chapters in international textbooks.
Dr. Sampath Chandra Prasad Rao's chapter ‘Extracranial Lateral Cranial Base Vascular Tumor Surgery’ in a textbook titled ‘Vascular Challenges in Skull Base Surgery’ published by University of Pittsburgh Skull Base Group.
Scrofula and other Tuberculous Infections in the Head & Neck
May 2018
Kishore Chandra Prasad • Sampath Chandra Prasad • Yeshwanth Chakravarthy • Pallavi Rao • Nikhil Thada • Smitha Rani
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Tuberculosis (TB) is an infection caused by Mycobacterium tuberculosis. It is a disease that has been known since antiquity but remains prevalent today, despite the availability of effective anti-TB antibiotics. In recent decades, the increasing prevalence of drug-resistant TB has complicated treatment. Untreated TB is deadly and carries a high mortality rate (70% for untreated smear-positive cases). The World Health Organization (WHO) reports that TB remains one of the top ten causes of death worldwide and caused 1.7 million deaths in 2015 alone. Early diagnosis of TB is essential, both for treating the infected patient and for preventing spread of TB to the community.
June 2019
Sampath Chandra Prasad • Alessandra Russo • Abdelkader Taibah • Francesco Galletti • Mario Sanna
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In this chapter, we provide a focused review on a highly challenging aspect of vestibular schwannoma surgery namely the facial nerve and its management.
June 2019
Sampath Chandra Prasad • Alessandra Russo • Abdelkader Taibah • Francesco Galletti • Mario Sanna
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In this chapter, we provide a detailed description of the Translabyrinthine Approach to vestibular Schwannomas
June 2019
Sampath Chandra Prasad • Carlo Terenzio Paties • Mattia Russel Pantalone • Renato Mariani-Costantini • Mario Sanna
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Carotid body and vagal paragangliomas, although considered indolent tumors, represent a challenge for the treating physician. This is mainly because of their peculiar localization, in close proximity with important anatomical structures. In addition, there is no chemotherapy available for these tumors, the role of radiation therapy is debated, and the only successful therapy is surgery. However, to achieve the best treatment goals, it is fundamental for the professional caregiver to master not only the clinical and surgical procedures but also the genetic backgrounds and the histopathological features of these tumors. We provide in this chapter a comprehensive review of the above mentioned aspects, with the aim to address the complexity of these tumors with a multidisciplinary approach.
June 2019
Sampath Chandra Prasad • Carlo Terenzio Paties • Francesca Schiavi • Diana Liberata Esposito • Lavinia Vittoria Lotti • Renato Mariani- Costantini4• Mario Sanna
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In this chapter, we provide a focused review on a highly challenging subset of head and neck paragangliomas, that is, those arising from the skull base (jugulotympanic region). Presently, these tumors can be cured only with surgery, which must be performed in highly specialized skull base surgical centers. We review here the clinical presentation, diagnostic workup, classification, and surgical management of these rare but important tumors, together with currently available evidence concerning genetics, developmental origin, and pathology.
February 2019
Sampath Chandra Prasad, Melissa Laus, Saeed Al-Ghamdi, Ashish Vashishth, Paolo Piazza P, Mario Sanna
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The proposed classification enables the clinician to plan the management of the ICA and the right approach. Stenting of the ICA gives a chance for complete tumor removal with arterial preservation.
February 2019
Manjunath Dandinarasiah, Sampath Chandra Prasad, Enrico Piccirillo, Mario Sanna
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Tumors of smaller sizes have good immediate postoperative FN results and recover well at the end of 1 year while more than 3 cm have poor outcomes and recover poorly at the end of 1 year. When the VSs reaches more than 1 cm, the HB I and II outcomes drop significantly.
November 2018
Sampath Chandra Prasad, Uma Patnaik, Golda Grinblat, Mario Sanna
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While there may be no price to pay in wait-and-scan as far as hearing is concerned, this may not be the case for facial nerve outcomes, wherein the results may be better if the patients are taken earlier for surgery.
Surgical Management of Class C and D Tympanojugular Paragangliomas
October 2018
Sampath Chandra Prasad, Paolo Piazza, Alessandra Russo​, Mario Sanna
Owing to the indolent nature of tympanojugular paragangliomas, they often present late with cranio-temporo-cervical extensions rendering them inoperable in the past. However, significant developments in the last couple of decades have changed this scenario. A thorough anatomical and surgical mapping of the skull base and descriptions of various rational approaches, in addition to technological improvements in neuromonitoring, neuroanesthesia, and neuroradiology, have made surgical removal of skull base tumors technically feasible and safer.
Surgical Management of Intrinsic Tumors of the Facial Nerve
October 2018
Sampath Chandra Prasad, Melissa Laus, Manjunath Dandinarasaiah, Mario Sanna
In patients with good facial nerve function (HB grade I-II), a wait-and-scan approach is recommended. In cases where the facial nerve has been interrupted during surgery, the cable nerve interpositioning technique is a convenient and well-accepted procedure for immediate restitution of the nerve.
Management of Internal Carotid Artery in Skull Base Paraganglioma Surgery
October 2018
Sampath Chandra Prasad, Paolo Piazza, Alessandra Russo, Mario Sanna
Surgical technique and results of cable graft interpositioning of the facial nerve in lateral skull base surgeries
February 2018
Sampath Chandra Prasad, Karthikeyan Balasubramanian, Enrico Piccirillo, Mario Sanna
Cable graft interpositioning is a convenient and well-accepted procedure for immediate restoration of the FN. The study results, over a large number of patients, showed that the stitch-less fibrin glue-aided coaptation technique yields good results. The best possible postoperative result achieved was an HB Grade III. The chances of a good postoperative result increase when FN function is normal preoperatively. Slow-growing tumors of the cerebellopontine angle had a favorable outcome after grafting.
Subtotal Petrosectomy: Surgical technique, indications, outcomes, and comprehensive review of literature
December 2017
Sampath Chandra Prasad, Valeria Roustan, Gianluca Piras, Mario Sanna
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Subtotal Petrosectomy is a very useful and safe surgical tool in the management of a variety of problematic situations in otology, as it offers the possibility of a definitive cure by offering radical clearance. This procedure can be combined safely with hearing implantation procedures.
Clinical and Surgical Pathology of the Petrous Apex
January 2017
Sampath Chandra Prasad, Mario Sanna
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The petrous apex is a pyramid shaped part of the temporal bone that is surrounded by the brain, complex neurovascular structures, and the organ of hearing. Diseases affecting the PA not only tend to have serious morbidities due to the affliction of important structures in the vicinity, but they are also difficult to approach surgically due to the deep location in the skull base. The presence of the internal carotid artery (ICA) and the facial nerve in the close vicinity adds to the surgical challenge. The treating surgeon must have a thorough understanding of the anatomy, clinical pathology, and skull base approaches to effectively deal with such lesions.
Surgical Strategy and Facial Nerve Outcomes in Petrous Bone Cholesteatoma
October 2016
Sampath Chandra Prasad, Gianluca Piras, Enrico Piccirillo, Mario Sanna
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Radical disease clearance must take precedence over hearing and FN preservation in PBCs. Active FN management, including rerouting, end-to-end anastomosis, and cable nerve grafting, routinely come to play in the surgical management of PBCs, and the postoperative FN results after such interventions can be satisfactory in most cases.
Lateral skull base approaches in the management of benign parapharyngeal space tumors
September 2014
Sampath Chandra Prasad, Enrico Piccirillo, MartinChovanec, MarioSanna
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Lateral skull base approaches have an advantage over other approaches in the management of benign tumors of the parapharyngeal space due to the fact that they provide excellent exposure with less morbidity. The use of microscope combined with bipolar cautery reduces morbidity. Stenting of internal carotid artery gives a chance for complete tumor removal with arterial preservation.
Long-term surgical and functional outcomes of the intact canal wall technique for middle ear cholesteatoma in the paediatric population
October 2014
Sampath Chandra Prasad, Claudio LA Melia, Marimar Medina, E Pasanisi
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The rate of residual cholesteatoma tends to decrease as age increases. The type of cholesteatoma, acquired or congenital middle ear, were not statistically related to the incidence of residual cholesteatoma. Hearing analysis showed that hearing recovery was excellent with canal wall up procedures and remained stable over five years.
Osteomyelitis of the Temporal Bone: Terminology, Diagnosis, and Management
June 2014
Sampath Chandra Prasad, Kishore Chandra Prasad, Abhijit Kumar, Satyanarayana Chalasani
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A new classification of temporal bone osteomyelitis has been proposed. Bacterial cultures must be performed in all patients. Antibiotic therapy is the treatment of choice. Surgical intervention is necessary in the presence of severe pain, complications, refractory cases, or the presence of bony sequestra on radiology.
The Role of Wait-and-Scan and the Efficacy of Radiotherapy in the Treatment of Temporal Bone Paragangliomas
April 2014
Sampath Chandra Prasad, Hassen Ait Mimoune, Flavia D'Orazio, Mario Sanna
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A literature review of the results of RT did not conclusively prove that it was effective as a primary modality of treatment for temporal bone paragangliomas. In elderly patients with advanced tumors, a wait-and-scan approach is recommended, and RT is initiated only when fast-growing tumors are detected. There is insufficient evidence in literature to suggest that RT could be an effective alternative to surgery in Class C and D tumors.
THIEME TEXTBOOK
Surgery for Cochlear and Other Auditory Implants
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Review by Otology & Neurotology:
This comprehensive, high-level surgical reference and atlas is tailored for surgeons who are undertaking training for cochlear implant procedures and implantable auditory devices and for experienced surgeons who would like to expand their knowledge, improve their skills and outcomes, and learn advanced surgical techniques. Supplementing the 1200 images within the book are 15 outstanding videos available on Thieme's MediaCenter
...an in-depth, thoughtful, and beautifully illustrated text....It is a notable and valuable addition...and represents the capacious collective experience of an accomplished, talented group of international implant surgeons.
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Review by Doody's Book Review (starred review)
The best feature of this book is the extensive pictorial representation of anatomy and the procedure, down to the specific instruments that are needed. The book clearly explains the surgery and how to do it, which is the goal.
Molecular biological studies on Paragangliomas
Pathbreaking research on the genesis of paragangliomas
Dr. Rao is a member of a multi-centric team that have been working on understanding the molecular basis of the origin of paragangliomas. Their path breaking findings have been published in prestigious peer-reviewed journals with very high impact factor
